Investigating the effect of an identified mutation within a critical site of PAS domain of WalK protein in a vancomycin-intermediate resistant Staphylococcus aureus by computational approaches
Abstract Background Vancomycin-intermediate resistant Staphylococcus aureus (VISA) is becoming a common cause of nosocomial infections worldwide.VISA isolates are developed by unclear molecular mechanisms via mutations in several genes, including walKR.Although studies have verified some of these mutations, there are a few studies that pay attentio